Up to 100 g of Intravenous Vitamin C Appears to be Safe and Elicits No Adverse Effects but Needs Further Evaluation in High-Risk Groups

Clin Pharmacokinet. 2022 Sep;61(9):1199-1202. doi: 10.1007/s40262-022-01156-9. Epub 2022 Jul 30.

Authors

Patrick M Honore¹, Sydney Blackman², Ibrahim Bousbiat², Emily Perriens², Rachid Attou²

Affiliations

¹ ICU Department, Centre Hospitalier Universitaire Brugmann-Brugmann University Hospital, ULB University, Place Van Gehuchtenplein, 4, 1020, Brussels, Belgium. Patrick.Honore@CHU-Brugmann.be.
² ICU Department, Centre Hospitalier Universitaire Brugmann-Brugmann University Hospital, ULB University, Place Van Gehuchtenplein, 4, 1020, Brussels, Belgium.

PMID: 35908007
DOI: 10.1007/s40262-022-01156-9

No abstract available

Keywords: AKI; CRRT; G6PD; High-dose vitamin; No adverse effects; Other side effects; Safe; Septic shock; Vitamin inducing AKI.

Publication types

Comment

MeSH terms

Acute Kidney Injury*
Administration, Intravenous
Ascorbic Acid* / adverse effects
Humans
Renal Replacement Therapy

Substances

Ascorbic Acid