C(sp3)-H oxidation and chlorination catalysed by a bioinspired pincer iron(III) complex

Dalton Trans. 2022 Aug 9;51(31):11620-11624. doi: 10.1039/d2dt02005j.

Abstract

A pincer iron(III) catalyst for the oxidation and chlorination of C(sp3)-H bonds was developed. Oxidation of a diagnostic substrate cis-decalin implies that a long-lived carbon-centred radical is involved. Mechanistic studies suggest that an Fe-oxo species could be responsible for the rate-determining C-H activation step. This report expands the scope of non-heme catalysts for C-H functionalisation.

MeSH terms

  • Carbon / chemistry
  • Catalysis
  • Halogenation*
  • Iron* / chemistry
  • Oxidation-Reduction

Substances

  • Carbon
  • Iron