Role of Placental Extracts in Periodontal Regeneration: A Literature Review

Cureus. 2022 Jun 17;14(6):e26042. doi: 10.7759/cureus.26042. eCollection 2022 Jun.

Abstract

Periodontium is a specialized tissue surrounding the teeth. It is made up of the gingiva, periodontal ligament, cementum, and alveolar bone. The healing of periodontal tissues when infected occurs through repair and regeneration. The central dogma of regenerative periodontics is to stimulate a cascade of healing events that, if coordinated well, can lead to proper tissue synthesis which in turn would play a very important part in managing periodontitis and preventing tooth loss. Many regenerative procedures are being followed in periodontics using newer and modified barrier membranes. Placental membranes like amnion, chorion and amnion-chorion membranes are one among these that serve the purpose because of their active components and therapeutic effects. This literature review highlights the benefits of placental extracts in regenerative periodontal therapy.

Keywords: amnion membrane; chorion membrane; periodontal regeneration; placentrex gel; tissue engineering.

Publication types

  • Review