Emerging threats and vaccination strategies of H9N2 viruses in poultry in Indonesia: A review

F1000Res. 2022 May 19:11:548. doi: 10.12688/f1000research.118669.2. eCollection 2022.

Abstract

Avian influenza virus subtype H9N2 was first documented in Indonesia in 2017. It has become prevalent in chickens in many provinces of Indonesia as a result of reassortment in live bird markets. Low pathogenic avian influenza subtype H9N2 virus-infected poultry provides a new direction for the influenza virus. According to the latest research, the Indonesian H9N2 viruses may have developed through antigenic drift into a new genotype, posing a significant hazard to poultry and public health. The latest proof of interspecies transmission proposes that the next human pandemic variant will be the avian influenza virus subtype H9N2. Manipulation and elimination of H9N2 viruses in Indonesia, constant surveillance of viral mutation, and vaccine updates are required to achieve effectiveness. The current review examines should be investigates/assesses/report on the development and evolution of newly identified H9N2 viruses in Indonesia and their vaccination strategy.

Keywords: Indonesia; avian influenza; emergence; public health; vaccination.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chickens
  • Humans
  • Indonesia
  • Influenza A Virus, H9N2 Subtype* / genetics
  • Influenza in Birds* / epidemiology
  • Influenza in Birds* / prevention & control
  • Poultry
  • Vaccination / veterinary

Grants and funding

This article was supported in part by the Penelitian Hibah Mandat funding from Universitas Airlangga, Indonesia in the fiscal year 2022, with grant number: 220/UN3.15/PT/2022.