TET2 deficiency exacerbates nasal polypogenesis by inducing epithelial-to-mesenchymal transition

Allergy. 2022 Nov;77(11):3452-3455. doi: 10.1111/all.15446. Epub 2022 Jul 25.

Authors

Peiqiang Liu¹, Danxue Qin¹, Zhifeng Deng¹, Xiaoting Tong¹, Kunyu Liu¹, Wenjun Fan¹, Jingyu Huang¹, Huiqin Zhou¹, Wanyang Gong¹, Jing Jin¹, Hao Lv¹, Siyuan Chen¹, Zezhang Tao^{1

2}, Yu Xu^{1

2}

Affiliations

¹ Department of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, China.
² Research Institute of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, China.

PMID: 35844041
DOI: 10.1111/all.15446

No abstract available

Keywords: CRS; EMT; PPAR-γ; TET2; nasal polyps.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Chronic Disease
DNA-Binding Proteins / genetics
Dioxygenases*
Epithelial-Mesenchymal Transition / genetics
Humans
Nasal Mucosa / pathology
Nasal Polyps* / pathology
Rhinitis* / pathology

Substances

TET2 protein, human
DNA-Binding Proteins
Dioxygenases