Cardiac events and economic burden among patients with hypertension and treated insomnia in the USA

Future Cardiol. 2022 Sep;18(9):731-741. doi: 10.2217/fca-2022-0009. Epub 2022 Jul 5.

Abstract

Background: Cardiovascular (CV) event risk, healthcare resource utilization (HCRU) and costs have not been elucidated among hypertension patients with treated insomnia (H + TI). Materials & methods: Adult patients with H + TI were identified in IBM MarketScan databases. H + TI patients were matched 1:1 on age and sex to controls with hypertension but without sleep disorders. Multivariable models were used to estimate associations between treated insomnia and CV event risk, HCRU and costs. Results: In total, 81,502 H + TI patients (mean age = 62 years, 53% female) were matched. Relative to controls, H + TI patients were 2.4 times as likely to have CV events. H + TI patients incurred higher costs per patient per month (US$2343 vs US$1013). Conclusion: Treated insomnia was associated with higher costs and HRCU in hypertension patients.

Keywords: comparative effectiveness; cost; healthcare utilization; hypertension; insomnia.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Female
  • Financial Stress
  • Humans
  • Hypertension* / epidemiology
  • Male
  • Middle Aged
  • Patient Acceptance of Health Care
  • Retrospective Studies
  • Sleep Initiation and Maintenance Disorders* / epidemiology
  • United States / epidemiology