1 Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; The Raymond G. Perelman Center for Cellular and Molecular Therapeutics, The Children's Hospital of Philadelphia, 5028 Colket Translational Research Center 3501 Civic Center Blvd., Philadelphia, PA 19104, USA; Department of Pediatrics, Division of Hematology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: samelsonjonesb@chop.edu.