Effect of the host genotype at a Porcine Reproductive and Respiratory Syndrome (PRRS) resistance marker on evolution of the modified-live PRRS vaccine virus in pigs

Raymond R R Rowland; Tyler Doerksen; Andrea Lu; Maureen Sheahan; Joan Lunney; Jack Dekkers; Rachel M Palinski

doi:10.1016/j.virusres.2022.198809

Effect of the host genotype at a Porcine Reproductive and Respiratory Syndrome (PRRS) resistance marker on evolution of the modified-live PRRS vaccine virus in pigs

Virus Res. 2022 Jul 15:316:198809. doi: 10.1016/j.virusres.2022.198809. Epub 2022 May 11.

Authors

Raymond R R Rowland¹, Tyler Doerksen², Andrea Lu², Maureen Sheahan², Joan Lunney³, Jack Dekkers⁴, Rachel M Palinski⁵

Affiliations

¹ Department of Pathobiology, College of Veterinary Medicine, University of Illinois, Champaign-Urbana, IL, United States.
² Veterinary Diagnostic Laboratory, College of Veterinary Medicine, Kansas State University, 2005 Research Park Circle, Manhattan, KS 66506, United States.
³ USDA, ARS, BARC, Animal Parasitic Diseases Laboratory, Beltsville, MD, United States.
⁴ Department of Animal Science, Iowa State University, Ames, IA, United States.
⁵ Veterinary Diagnostic Laboratory, College of Veterinary Medicine, Kansas State University, 2005 Research Park Circle, Manhattan, KS 66506, United States; Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, United States. Electronic address: rpalinski@vet.k-state.edu.

PMID: 35568091
DOI: 10.1016/j.virusres.2022.198809

Abstract

Porcine reproductive and respiratory syndrome; Porcine reproductive and respiratory syndrome virus; PRRS; Whole genome sequencing; Quasispecies; WUR allele.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Alleles
Animals
Genotype
Porcine Reproductive and Respiratory Syndrome* / prevention & control
Porcine respiratory and reproductive syndrome virus* / genetics
Swine
Viral Vaccines*

Substances

Viral Vaccines