Clinical relevance of dual agonist of glucagon and glucagon-like peptide-1 receptors to achieve functional restoration of first- and second-phase insulin secretion

J Diabetes Investig. 2022 Aug;13(8):1300-1302. doi: 10.1111/jdi.13831. Epub 2022 Jun 2.

Authors

Tomohiko Kimura¹, Kohei Kaku¹

Affiliation

¹ Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Kurashiki, Japan.

Abstract

The role of glucagon and GLP-1 receptors in first and second phase insulin secretion.

© 2022 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd.

MeSH terms

Glucagon* / metabolism
Glucagon-Like Peptide 1
Glucagon-Like Peptide-1 Receptor*
Humans
Insulin / metabolism
Insulin Secretion
Peptide Fragments
Receptors, Glucagon / agonists
Receptors, Glucagon / metabolism

Substances

Glucagon-Like Peptide-1 Receptor
Insulin
Peptide Fragments
Receptors, Glucagon
Glucagon-Like Peptide 1
Glucagon