Household air pollution from solid fuel use as a dose-dependent risk factor for cognitive impairment in northern China

Sci Rep. 2022 Apr 13;12(1):6187. doi: 10.1038/s41598-022-10074-6.

Abstract

The relationship between exposure to household air pollution (HAP) from solid fuel use and cognition remains poorly understood. Among 401 older adults in peri-urban northern China enrolled in the INTERMAP-China Prospective Study, we estimated the associations between exposure to HAP and z-standardized domain-specific and overall cognitive scores from the Montreal Cognitive Assessment. Interquartile range increases in exposures to fine particulate matter (53.2-µg/m3) and black carbon (0.9-µg/m3) were linearly associated with lower overall cognition [- 0.13 (95% confidence interval: - 0.22, - 0.04) and - 0.10 (- 0.19, - 0.01), respectively]. Using solid fuel indoors and greater intensity of its use were also associated with lower overall cognition (range of point estimates: - 0.13 to - 0.03), though confidence intervals included zero. Among individual cognitive domains, attention had the largest associations with most exposure measures. Our findings indicate that exposure to HAP may be a dose-dependent risk factor for cognitive impairment. As exposure to HAP remains pervasive in China and worldwide, reducing exposure through the promotion of less-polluting stoves and fuels may be a population-wide intervention strategy to lessen the burden of cognitive impairment.

MeSH terms

  • Aged
  • Air Pollution / analysis
  • Air Pollution / statistics & numerical data
  • Air Pollution, Indoor* / analysis
  • Air Pollution, Indoor* / statistics & numerical data
  • China / epidemiology
  • Cognitive Dysfunction* / epidemiology
  • Cognitive Dysfunction* / etiology
  • Cooking
  • Environmental Exposure / analysis
  • Environmental Exposure / statistics & numerical data
  • Humans
  • Prospective Studies
  • Risk Factors