Recalcitrant digital calcinosis cutis successfully treated with intralesional sodium thiosulfate under digital nerve blockade

BMJ Case Rep. 2022 Apr 6;15(4):e248707. doi: 10.1136/bcr-2021-248707.

Abstract

Dystrophic calcinosis cutis can be associated with severe pain, decreased mobility, increased risk of infection and significantly decreased quality of life. We report a case of recalcitrant calcinosis cutis on the background of eosinophilic fasciitis, which achieved rapid reduction in calcium deposits following a novel injecting protocol of intralesional sodium thiosulfate.

Keywords: Dermatology; Skin; Therapeutic indications.

Publication types

  • Case Reports

MeSH terms

  • Calcinosis* / complications
  • Calcinosis* / drug therapy
  • Humans
  • Nerve Block* / adverse effects
  • Quality of Life
  • Skin Diseases* / drug therapy
  • Skin Diseases* / etiology
  • Thiosulfates

Substances

  • Thiosulfates
  • sodium thiosulfate