Improvement of quality of life after 2-month exoskeleton training in patients with chronic spinal cord injury

J Spinal Cord Med. 2024 May;47(3):354-360. doi: 10.1080/10790268.2022.2052502. Epub 2022 Apr 4.

Abstract

Objective: To examine changes in quality of life (QoL) after an eight-week period of robotic exoskeleton training in a homogeneous group of patients with chronic complete spinal cord injury (SCI).

Design: Prospective single-group pre-post study.

Setting: Rehabilitation center.

Participants: Patients with a chronic (>6 months) motor complete SCI (T1-L1).

Intervention: Twenty-four training sessions with the ReWalk exoskeleton over an eight-week period.

Main outcome measure: QoL, assessed with the sum score of the Short Form-36 with Walk Wheel modification (SF-36ww). Secondary outcome measures were the eight SF-36ww subdomains, satisfaction with bladder and bowel management, lower extremity joint passive range of motion (pROM), and lower extremity spasticity.

Results: Twenty-one participants completed the training. QoL significantly improved after the training period (average SF-36 sum score 621 ± 90) compared to baseline (571 ± 133) (t(20)=-2.5, P=.02). Improvements were seen on the SF-36ww subdomains for pain (P=.003), social functioning (P=.03), mental health (P=.02), and general health perception (P=.01). Satisfaction with bladder management (range 1-5) improved from median 3 at baseline to 4 after exoskeleton training (P=0.01). No changes in satisfaction with bowel management (P=.11), pROM (hip-extension (P=.49), knee-extension (P=.36), ankle dorsiflexion (P=.69)), or spasticity (P=.94) were found.

Conclusion: Even in patients with chronic motor complete SCI and a relatively high level of QoL at baseline, a short-term exoskeleton training improved their QoL, pain and satisfaction with bladder management; findings that warrant further controlled studies in this specific SCI population.

Keywords: Health state; Powered exoskeleton; Quality of life; Spinal cord injury.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Chronic Disease
  • Exercise Therapy / methods
  • Exoskeleton Device*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Quality of Life*
  • Spinal Cord Injuries* / complications
  • Spinal Cord Injuries* / rehabilitation

Grants and funding

This work is part of the research program Wearable Robotics with project number P16-05, which is (partly) financed by the Dutch Research Council (NWO).