Trait Anger, Hostility, and the Risk of Type 2 Diabetes and Diabetes- Related Complications: A Systematic Review of Longitudinal Studies

Marzia Mohseni; Nanna Lindekilde; Geneviève Forget; Rachel J Burns; Frans Pouwer; Norbert Schmitz; Sonya S Deschênes

doi:10.2174/1573399818666220329185229

Trait Anger, Hostility, and the Risk of Type 2 Diabetes and Diabetes- Related Complications: A Systematic Review of Longitudinal Studies

Curr Diabetes Rev. 2023;19(4):e290322202789. doi: 10.2174/1573399818666220329185229.

Authors

Marzia Mohseni¹, Nanna Lindekilde², Geneviève Forget³, Rachel J Burns³, Frans Pouwer^{2

4}, Norbert Schmitz^{5

6}, Sonya S Deschênes¹

Affiliations

¹ School of Psychology, University College Dublin, Dublin, Ireland.
² Department of Psychology, University of Southern Denmark, Odense, Denmark.
³ Department of Psychology, Carleton University, Ottawa ON, Canada.
⁴ Steno Diabetes Center Odense, Odense, Denmark.
⁵ Department of Psychiatry, McGill University, Montreal, Quebec, Canada.
⁶ Department of Population-Based Medicine, University of Tuebingen, Tuebingen, Germany.

PMID: 35352665
DOI: 10.2174/1573399818666220329185229

Abstract

Background: Research suggests associations between trait anger, hostility, and type 2 diabetes and diabetes-related complications, though evidence from longitudinal studies has not yet been synthesized.

Objective: The present systematic review examined findings from longitudinal research on trait anger or hostility and the risk of incident type 2 diabetes or diabetes-related complications. The review protocol was pre-registered in PROSPERO (CRD42020216356).

Methods: Electronic databases (MEDLINE, PsychINFO, Web of Science, and CINAHL) were searched for articles and abstracts published up to December 15, 2020. Peer-reviewed longitudinal studies with adult samples, with effect estimates reported for trait anger/hostility and incident diabetes or diabetes-related complications, were included. Title and abstract screening, full-text screening, data extraction, and quality assessment using the Newcastle-Ottawa Scale were conducted by two independent reviewers. A narrative synthesis of the extracted data was conducted according to the Synthesis Without Meta-Analysis guidelines.

Results: Five studies (N = 155,146 participants) met the inclusion criteria. While results were mixed, our synthesis suggested an overall positive association between high trait-anger/hostility and an increased risk of incident diabetes. Only one study met the criteria for the diabetes-related complications outcome, which demonstrated a positive association between hostility and incident coronary heart disease but no significant association between hostility and incident stroke.

Conclusion: Based on the available longitudinal evidence, trait anger and hostility are associated with an increased risk of diabetes. Longitudinal studies are needed to investigate the association between trait-anger or hostility and the risk of diabetes-related complications.

Keywords: Anger; diabetes complications; hostility; prospective studies; systematic review; type 2 diabetes.

Publication types

Systematic Review

MeSH terms

Adult
Anger
Diabetes Mellitus, Type 2* / complications
Diabetes Mellitus, Type 2* / epidemiology
Hostility*
Humans
Longitudinal Studies
Risk Factors