Membrane trafficking: ESCRTs act here, there, and everywhere

Leticia Lemus; Veit Goder

doi:10.1016/j.cub.2022.02.043

Membrane trafficking: ESCRTs act here, there, and everywhere

Curr Biol. 2022 Mar 28;32(6):R292-R294. doi: 10.1016/j.cub.2022.02.043.

Authors

Leticia Lemus¹, Veit Goder²

Affiliations

¹ Department of Genetics, University of Seville, Av. Reina Mercedes 6, 41012 Seville, Spain. Electronic address: llemus@us.es.
² Department of Genetics, University of Seville, Av. Reina Mercedes 6, 41012 Seville, Spain. Electronic address: vgoder@us.es.

PMID: 35349820
DOI: 10.1016/j.cub.2022.02.043

Abstract

Endosomal sorting complex required for transport (ESCRT) proteins can promote extreme membrane deformations, including scission and sealing. New work uncovers a link between these proteins and the early secretory pathway that is functionally important for programmed autophagy during Drosophila development.

Publication types

Comment

MeSH terms

Autophagy
Endosomal Sorting Complexes Required for Transport* / metabolism
Endosomes* / metabolism
Protein Transport

Substances

Endosomal Sorting Complexes Required for Transport