Simple Setup Miniaturization with Multiple Benefits for Green Chemistry in Nanoparticle Synthesis

ACS Omega. 2022 Jan 25;7(5):4714-4721. doi: 10.1021/acsomega.2c00030. eCollection 2022 Feb 8.

Abstract

The development of nanomaterials often relies on wet-chemical synthesis performed in reflux setups using round-bottom flasks. Here, an alternative approach to synthesize nanomaterials is presented that uses glass tubes designed for NMR analysis as reactors. This approach uses less solvent and energy, generates less waste, provides safer conditions, is less prone to contamination, and is compatible with high-throughput screening. The benefits of this approach are illustrated by an in breadth study with the synthesis of gold, iridium, osmium, and copper sulfide nanoparticles.