Synovitis-acne-pustulosis-hyperostosis-osteitis Syndrome with Bilateral Pleural Effusion

Maho Adachi-Katayama; Yuya Kondo; Shota Okamoto; Ryota Sato; Satoshi Morinaka; Taihei Nishiyama; Mayu Terasaki; Toshihiko Terasaki; Hirofumi Toko; Mizuki Yagishita; Hiroyuki Takahashi; Shinya Hagiwara; Hiroto Tsuboi; Takayuki Sumida; Isao Matsumoto

doi:10.2169/internalmedicine.8473-21

Synovitis-acne-pustulosis-hyperostosis-osteitis Syndrome with Bilateral Pleural Effusion

Intern Med. 2022 Sep 1;61(17):2671-2675. doi: 10.2169/internalmedicine.8473-21. Epub 2022 Feb 8.

Authors

Affiliations

¹ Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan.
² Department of General Medicine, Mito Kyodo General Hospital, University of Tsukuba, Japan.

Abstract

Pleural effusion is a rare manifestation in synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome, which is characterized by the presence of osteoarticular lesions and dermatological involvement. We herein report a 71-year-old man with pleural effusion resulting from SAPHO syndrome. He was successfully treated using corticosteroids and has experienced no recurrence for one year. We should consider SAPHO syndrome when encountering cases of anterior chest pain and pleural fluid.

Keywords: SAPHO syndrome; anterior chest pain; hypoxia; pleural effusion.

Publication types

Case Reports

MeSH terms

Acne Vulgaris* / pathology
Acquired Hyperostosis Syndrome* / complications
Acquired Hyperostosis Syndrome* / diagnosis
Acquired Hyperostosis Syndrome* / drug therapy
Aged
Humans
Hyperostosis* / pathology
Male
Osteitis* / pathology
Pleural Effusion* / diagnostic imaging
Pleural Effusion* / etiology
Synovitis* / diagnosis
Synovitis* / diagnostic imaging