Vertically Aligned Carbon Nanotubes as a Unique Material for Biomedical Applications

ACS Appl Mater Interfaces. 2022 Feb 9;14(5):6287-6306. doi: 10.1021/acsami.1c20423. Epub 2022 Jan 28.

Abstract

Vertically aligned carbon nanotubes (VACNTs), a unique classification of CNT, highly oriented and normal to the respective substrate, have been heavily researched over the last two decades. Unlike randomly oriented CNT, VACNTs have demonstrated numerous advantages making it an extremely desirable nanomaterial for many biomedical applications. These advantages include better spatial uniformity, increased surface area, greater susceptibility to functionalization, improved electrocatalytic activity, faster electron transfer, higher resolution in sensing, and more. This Review discusses VACNT and its utilization in biomedical applications particularly for sensing, biomolecule filtration systems, cell stimulation, regenerative medicine, drug delivery, and bacteria inhibition. Furthermore, comparisons are made between VACNT and its traditionally nonaligned, randomly oriented counterpart. Thus, we aim to provide a better understanding of VACNT and its potential applications within the community and encourage its utilization in the future.

Keywords: diagnostics; drug delivery; sensors; therapeutics; tissue engineering; vertically aligned carbon nanotubes.

Publication types

  • Review

MeSH terms

  • Animals
  • Bacteria / drug effects
  • Biocompatible Materials / chemistry
  • Biocompatible Materials / pharmacology
  • Biosensing Techniques / methods
  • Carcinoembryonic Antigen / analysis
  • Cell Proliferation / drug effects
  • Drug Carriers / chemistry*
  • Humans
  • Nanotubes, Carbon / chemistry*
  • Nanotubes, Carbon / toxicity
  • Tissue Engineering*

Substances

  • Biocompatible Materials
  • Carcinoembryonic Antigen
  • Drug Carriers
  • Nanotubes, Carbon