Radiomics and Radiogenomics in Evaluation of Colorectal Cancer Liver Metastasis

Front Oncol. 2022 Jan 7:11:689509. doi: 10.3389/fonc.2021.689509. eCollection 2021.

Abstract

Colorectal cancer is one common digestive malignancy, and the most common approach of blood metastasis of colorectal cancer is through the portal vein system to the liver. Early detection and treatment of liver metastasis is the key to improving the prognosis of the patients. Radiomics and radiogenomics use non-invasive methods to evaluate the biological properties of tumors by deeply mining the texture features of images and quantifying the heterogeneity of metastatic tumors. Radiomics and radiogenomics have been applied widely in the detection, treatment, and prognostic evaluation of colorectal cancer liver metastases. Based on the imaging features of the liver, this paper reviews the current application of radiomics and radiogenomics in the diagnosis, treatment, monitor of disease progression, and prognosis of patients with colorectal cancer liver metastases.

Keywords: colorectal cancer; gene; liver metastasis; prognosis; radiomics; treatment.

Publication types

  • Review