Gastric MALT-Lymphoma: more than Helicobacter Pylori

Acta Gastroenterol Belg. 2021 Oct-Dec;84(4):657-659. doi: 10.51821/84.4.016.

Abstract

In this case report, we describe two cases of gastric mucosaassociated lymphoid tissue (MALT) lymphoma. The first patient, who presented with complaints of indigestion, nausea and epigastralgy, had a solid ulcer on endoscopy. Biopsies showed, next to MALT, presence of Helicobacter Pylori. The second patient was admitted with hematemesis. The multiple ulcerations in his stomach were thought to be cocaine-induced. Only after multiple biopsies the diagnosis of MALT was made. No presence of Helicobacter Pylori could be detected. The first patient was successfully treated with Helicobacter Pylori eradication therapy. Localized radiotherapy resulted in complete remission in our second patient. Hence, in absence of Helicobacter Pylori, more aggressive treatment modalities are needed.

Keywords: Helicobacter Pylori; MALT-lymphoma; eradication; stomach.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Helicobacter Infections* / diagnosis
  • Helicobacter Infections* / drug therapy
  • Helicobacter pylori*
  • Humans
  • Lymphoid Tissue
  • Lymphoma, B-Cell, Marginal Zone* / drug therapy
  • Lymphoma, B-Cell, Marginal Zone* / therapy
  • Stomach Neoplasms* / diagnosis
  • Stomach Neoplasms* / drug therapy

Substances

  • Anti-Bacterial Agents