Objective: To collate and analyze the screening results of high-risk lung cancer populations in communities in Nanchang from 2018 to 2019, and to explore the lung-positive nodules and risk factors for lung cancer. Methods: Data of the screening subjects in 8 administrative districts and 15 street health service centers in Nanchang city, Jiangxi province from November 2018 to October 2019 were collected, people at high risk of lung cancer was assessed, clinical screening of high-risk groups of lung cancer was conducted by low-dose helical computed tomography (LDCT), and risk factors for suspected lung cancer and lung-positive nodules were analyzed. Results: Of the 25 871 people participated in screening, 5 220 were at high risk for lung cancer and 15 374 without other malignant tumors were at high risk. There were 2 417 cases participated in clinical LDCT screening, including 193 cases of lung-positive nodules, 67 cases of suspected lung cancer, 912 cases of other lung diseases, the positive rate of lung cancer or lung-positive nodules was 10.76% (260/2 417). Univariate analysis showed that age, coarse grain intake, oil intake, housing heating, passive smoking, alcohol consumption and mental trauma were associated with positive pulmonary nodules or lung cancer (all P<0.05). Multivariate analysis showed that gender, age, housing heating, smoking and drinking were related to the occurrence of lung nodules or lung cancer (all P<0.05). Conclusions: Men are more likely to develop lung cancer or lung-positive nodules than women. The age is an independent risk factor for lung-positive nodules or lung cancer. In a certain range, age will increase the incidence of lung cancer, housing heating may be the protective factor for lung cancer, while smoking and drinking are risk factors.
目的： 分析2018—2019年南昌市社区肺癌高危人群筛查结果，探讨肺阳性结节和肺癌的危险因素。 方法： 收集2018年11月至2019年10月江西省南昌市8个行政区、15个街道卫生服务中心的所有筛查对象的资料，评估肺癌高风险人群，对肺癌高风险人群进行低剂量螺旋CT临床筛查，分析疑似肺癌和肺阳性结节患者的危险因素。 结果： 评估参加筛查的25 871例人群中，肺癌高危人群为5 220例，无其他恶性肿瘤高危风险人数为15 374例。参加临床低剂量螺旋CT筛查2 417例，其中肺阳性结节193例，疑似肺癌67例，其他肺部疾病912例，肺癌或肺阳性结节的阳性率为10.76%(260/2 417)。单因素分析显示，年龄、粗粮摄入、油脂摄入、住房取暖、被动吸烟、饮酒和精神创伤与肺结节阳性或肺癌的发生有关(均P<0.05)。多因素分析显示，性别、年龄、住房取暖、吸烟和饮酒与肺结节或肺癌的发生有关(均P<0.05)。 结论： 男性较女性患肺癌或肺阳性结节风险更高，年龄是肺阳性结节或肺癌独立危险因素，在一定范围内，年龄增长会增加肺癌的发病率，住房取暖可能是肺癌发病的保护因素，吸烟、饮酒是肺癌发病的危险因素。.
Keywords: Early screening; High risk population; Lung neoplasms; Pulmonary nodule; Risk factor.