Currently, there is no single technology capable of assessing all the multitude of factors associated with peripheral complications of diabetic neuropathy. In this work, a multimodal wound detection system is proposed to help facilitate in-home examinations, utilizing a combination of thermal, multi-spectral 3D imaging modalities. The proposed system is capable of the 3D surface rendering of the foot and would overlay thermal, blood oxygenation, besides other skin health information to aid with foot health monitoring. Examples of biomarkers include pre-ulcer formation, blood circulation, temperature change, oxygenation, swelling, blisters/ulcer formation and healing, and toe health.