Lysinibacillus fusiformis bacteremia: Case report and literature review

J Infect Chemother. 2022 Feb;28(2):315-318. doi: 10.1016/j.jiac.2021.10.030. Epub 2021 Dec 2.

Abstract

A 93-year-old woman was diagnosed with Lysinibacillus fusiformis bacteremia complicated with coma blisters. Initial gram staining for L. fusiformis indicated the presence of gram-negative rods; however, subsequent staining of colonies from Mueller-Hinton agar revealed the presence of gram-positive and gram-negative rods with spherical endospores, and Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (VITEK ® MS and microflex® LT/SH) definitively identified the organism as L. fusiformis. The two-week administration of piperacillin/tazobactam and ampicillin resulted in an improvement of the patient's general condition, and the skin lesions gradually improved.

Keywords: Bacillus fusiformis; Coma blister; Gram-variable organism; Lysinibacillus fusiformis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged, 80 and over
  • Bacillaceae*
  • Bacteremia* / diagnosis
  • Bacteremia* / drug therapy
  • Female
  • Gram-Negative Bacteria
  • Humans
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Supplementary concepts

  • Lysinibacillus fusiformis