Ciprofloxacin-associated Peripheral Neuropathy in a Child: A Case Report and Review of the Literature

Pediatr Infect Dis J. 2022 Feb 1;41(2):121-122. doi: 10.1097/INF.0000000000003373.

Abstract

Fluoroquinolones are reported to have peripheral nerve toxic effects that can be severe and permanent in adults. However, limited data exist for children. We describe a case of acute-onset peripheral neuropathy associated with ciprofloxacin in a 13-year-old boy who was characterized by severe dysesthesia and erythema of both hands and feet, but which resolved promptly after ceasing the antibiotic.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents / adverse effects*
  • Anti-Bacterial Agents / therapeutic use
  • Ciprofloxacin / adverse effects*
  • Ciprofloxacin / therapeutic use
  • Erythema / chemically induced
  • Foot / physiopathology
  • Hand / physiopathology
  • Humans
  • Male
  • Osteomyelitis / drug therapy
  • Osteomyelitis / surgery
  • Peripheral Nervous System Diseases / chemically induced*
  • Sinusitis / drug therapy
  • Sinusitis / surgery

Substances

  • Anti-Bacterial Agents
  • Ciprofloxacin