Successful management of Aspergillus infection of an open window thoracostomy with topical liposomal amphotericin B

Alexis Legault-Dupuis; France-Emilie Roy; Isabelle Giroux; Michelle Bernard-Genest; Florence Cote; Anne-Sophie Laliberte

doi:10.1016/j.mmcr.2021.08.004

Successful management of Aspergillus infection of an open window thoracostomy with topical liposomal amphotericin B

Med Mycol Case Rep. 2021 Aug 17:34:38-41. doi: 10.1016/j.mmcr.2021.08.004. eCollection 2021 Dec.

Authors

Alexis Legault-Dupuis¹, France-Emilie Roy¹, Isabelle Giroux¹, Michelle Bernard-Genest¹, Florence Cote¹, Anne-Sophie Laliberte¹

Affiliation

¹ Institut Universitaire de cardiologie et pneumologie de Québec- Université Laval, 2725, Chemin Ste-Foy, Quebec, Qc, Canada, G1V 4G5.

Abstract

We present the case of a previously healthy 54-year-old man who was hospitalized for an Aspergillus fumigatus infection of an open window thoracotomy. Patient was successfully treated for 8 consecutives weeks with daily topical pleural liposomal amphotericine B administered by soaked gauzes combined with systemic therapy.

Keywords: Aspergillus; Empyema; Open window thoracotomy; Pleural antifungal therapy.

Publication types

Case Reports