Acute interstitial nephritis secondary to vedolizumab

BMJ Case Rep. 2021 Nov 19;14(11):e243568. doi: 10.1136/bcr-2021-243568.

Abstract

We present a patient with an acute kidney injury thought secondary to acute interstitial nephritis as a result of vedolizumab maintenance therapy for Crohn's disease. This appears to be a rare but serious side effect in patients receiving this treatment which clinicians should consider in the event of renal dysfunction.

Keywords: Crohn's disease; acute renal failure; renal system; unwanted effects/adverse reactions.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Monoclonal, Humanized / adverse effects
  • Crohn Disease* / drug therapy
  • Humans
  • Nephritis, Interstitial* / chemically induced

Substances

  • Antibodies, Monoclonal, Humanized
  • vedolizumab