Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia: clinical characteristics and progression to carcinoid tumour

Thomas Yang Sun; Grace Hwang; Danielle Pancirer; Kathleen Hornbacker; Alberto Codima; Natalie S Lui; Rishi Raj; Pamela Kunz; Sukhmani K Padda

doi:10.1183/13993003.01058-2021

Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia: clinical characteristics and progression to carcinoid tumour

Eur Respir J. 2022 Jan 27;59(1):2101058. doi: 10.1183/13993003.01058-2021. Print 2022 Jan.

Authors

Affiliations

¹ Stanford University School of Medicine, Division of Oncology, Dept of Medicine, Stanford, CA, USA.
² Stanford University School of Medicine, Dept of Cardiothoracic Surgery, Stanford, CA, USA.
³ Stanford University School of Medicine, Division of Pulmonary and Critical Care Medicine, Dept of Medicine, Stanford, CA, USA.
⁴ Yale School of Medicine, Smilow Cancer Hospital, Yale Cancer Center, New Haven, CT, USA.
⁵ Stanford University School of Medicine, Division of Oncology, Dept of Medicine, Stanford, CA, USA Sukhmani.Padda@cshs.org.
⁶ Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Abstract

DIPNECH is a rare disease that is often misdiagnosed. In this study, it primarily affected elderly white women who were non-smokers. Lung nodules could slowly progress over years to carcinoid tumours. Average growth rate per nodule was 0.8 mm per year. https://bit.ly/3q1HD1k

Publication types

Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Carcinoid Tumor* / diagnosis
Humans
Hyperplasia
Lung / diagnostic imaging
Lung / pathology
Lung Neoplasms* / pathology
Neuroendocrine Cells* / pathology

Abstract

Publication types

MeSH terms

Grants and funding