Glutamate correlates negatively with cognitive theory of mind in schizotypy

Si-Yu Chen; Ling-Ling Wang; Gai-Ying Li; Yi Wang; Min-Yi Chu; Chao Yan; Simon S Y Lui; Jian-Qi Li; Raymond C K Chan

doi:10.1002/pchj.503

Glutamate correlates negatively with cognitive theory of mind in schizotypy

Psych J. 2022 Jun;11(3):356-358. doi: 10.1002/pchj.503. Epub 2021 Nov 18.

Authors

Si-Yu Chen^{1

2}, Ling-Ling Wang^{1

2}, Gai-Ying Li³, Yi Wang^{1

2}, Min-Yi Chu⁴, Chao Yan⁵, Simon S Y Lui⁶, Jian-Qi Li³, Raymond C K Chan^{1

2}

Affiliations

¹ Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China.
² Department of Psychology, University of Chinese Academy of Sciences, Beijing, China.
³ Shanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, Shanghai, China.
⁴ Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
⁵ Key Laboratory of Brain Functional Genomics (MOE&STCSM), Shanghai Changning-ECNU Mental Health Center, School of Psychology and Cognitive Science, East China Normal University, Shanghai, China.
⁶ Department of Psychiatry, The University of Hong Kong, Hong Kong SAR, China.

PMID: 34794205
DOI: 10.1002/pchj.503

Abstract

This study showed a negative correlation between the glutamate level in the anterior cingulate cortex and cognitive theory of mind in individuals with high level of schizotypy but not in non-schizotypy individuals.

Keywords: glutamate; magnetic resonance spectroscopy (MRS); schizotypy; social cognition; theory of mind.

MeSH terms

Cognition
Glutamic Acid
Gyrus Cinguli
Humans
Schizotypal Personality Disorder* / psychology
Theory of Mind*

Substances

Glutamic Acid

Abstract

MeSH terms

Substances

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