Protein-protein interactions at a glance: Protocols for the visualization of biomolecular interactions

Abstract

Protein-protein interactions (PPIs) play a key role in many biological processes and are intriguing targets for drug discovery campaigns. Advancements in experimental and computational techniques are leading to a growth of data accessibility, and, with it, an increased need for the analysis of PPIs. In this respect, visualization tools are essential instruments to represent and analyze biomolecular interactions. In this chapter, we reviewed some of the available tools, highlighting their features, and describing their functions with practical information on their usage.

Keywords: 3D representation; Molecular interactions; Protein; Protein interface; Protein photorealism; Protein-protein interactions; Surface.