Spontaneous arising of a lymphoblastoid B-cell line harbouring a pre-leukemic DNMT3A mutation in acute myeloid leukaemia cell culture

J Cell Mol Med. 2021 Nov;25(22):10778-10782. doi: 10.1111/jcmm.16992. Epub 2021 Oct 14.

Michal Hayun¹, Moran Szwarcwort², Dina Rosenberg³, Dvora Sahar³, Yishai Ofran^{1

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¹ The Clinical Research Institute at Rambam (CRIR), Rambam Health Care Campus, Haifa, Israel.
² Virology Laboratory, Rambam Health Care Campus, Haifa, Israel.
³ Hematology Laboratory, Rambam Health Care Campus, Haifa, Israel.
⁴ Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel.
⁵ Department of Hematology, Shaare Zedek Medical Center, Faculty of Medicine, the Hebrew University of Jerusalem, Jerusalem, Israel.

No abstract available

Keywords: B-cell functions; DNMT3A; acute myeloid leukaemia; pre-leukemic mutations; spontaneously arising lymphoblastoid cell line.

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