What's the use?

Elife. 2021 Oct 12:10:e73193. doi: 10.7554/eLife.73193.

Authors

Jason M Fletcher^{1

2

3}, Yuchang Wu^{3

4}, Qiongshi Lu^{3

4}

Affiliations

¹ Department of Sociology, University of Wisconsin-Madison, Madison, United States.
² La Follette School of Public Affairs, University of Wisconsin-Madison, Madison, United States.
³ Center for Demography of Health and Aging, University of Wisconsin-Madison, Madison, United States.
⁴ Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, United States.

Abstract

A theoretical framework predicts that using polygenic screening to select embryos against traits that depend on many genes has few benefits.

Keywords: embryo; genetics; genomics; human; in vitro fertilization; polygenic risk scores; preimplantation genetic testing.

© 2021, Fletcher et al.

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MeSH terms

Multifactorial Inheritance*
Phenotype