Novel Mechanisms of Exosome-Mediated Phagocytosis of Dead Cells in Injured Heart

Circ Res. 2021 Nov 12;129(11):1006-1020. doi: 10.1161/CIRCRESAHA.120.317900. Epub 2021 Oct 8.

Abstract

[Figure: see text].

Keywords: RNA, small interfering; exosomes; mesenchymal stem cells; opsonin proteins; phosphatidylserines.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antigens, Surface / genetics
  • Antigens, Surface / metabolism
  • Apoptosis*
  • Cells, Cultured
  • Exosomes / metabolism*
  • Integrins / metabolism
  • Macrophages / metabolism
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Milk Proteins / genetics
  • Milk Proteins / metabolism
  • Myocardial Ischemia / metabolism*
  • Myocytes, Cardiac / metabolism
  • Phagocytosis*
  • RAW 264.7 Cells

Substances

  • Antigens, Surface
  • Integrins
  • Mfge8 protein, mouse
  • Milk Proteins