Epigenetic fun(ction) in the sun

Megan He; Brian Raftrey; Ya-Chieh Hsu

doi:10.1016/j.devcel.2021.09.004

Epigenetic fun(ction) in the sun

Dev Cell. 2021 Sep 27;56(18):2537-2539. doi: 10.1016/j.devcel.2021.09.004.

Authors

Megan He¹, Brian Raftrey², Ya-Chieh Hsu³

Affiliations

¹ Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA; Harvard Stem Cell Institue, Cambridge, MA 02138, USA; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.
² Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA; Harvard Stem Cell Institue, Cambridge, MA 02138, USA.
³ Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA; Harvard Stem Cell Institue, Cambridge, MA 02138, USA. Electronic address: yachieh_hsu@harvard.edu.

PMID: 34582768
DOI: 10.1016/j.devcel.2021.09.004

Abstract

Tanning, or increased epidermal pigmentation, protects organisms from ultraviolet radiation (UV)-induced damages. In this issue of Development Cell, Li et al. demonstrate a key role for a chromatin regulator-the Polycomb complex-in epidermal stem cells (EpSCs) in mediating UV-induced tanning responses and epidermal pigmentation.

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MeSH terms

Epidermis*
Epigenesis, Genetic
Ultraviolet Rays*