Environmental Factors

Katherine D Wick; Michael A Matthay

doi:10.1016/j.ccc.2021.05.002

Environmental Factors

Crit Care Clin. 2021 Oct;37(4):717-732. doi: 10.1016/j.ccc.2021.05.002.

Authors

Katherine D Wick¹, Michael A Matthay²

Affiliations

¹ Department of Anesthesia, University of California, San Francisco, 513 Parnassus Avenue, HSE 760, San Francisco, CA 94143, USA; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA.
² Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA; Department of Medicine, University of California, San Francisco, 505 Parnassus Avenue, M-917, San Francisco, CA 94143, USA; Department of Anesthesia, University of California, San Francisco, 505 Parnassus Avenue, M-917, San Francisco, CA 94143, USA. Electronic address: Michael.matthay@ucsf.edu.

Abstract

The acute respiratory distress syndrome (ARDS) remains a major cause of morbidity and mortality in the intensive care unit. Improving outcomes depends on not only evidence-based care once ARDS has already developed but also preventing ARDS incidence. Several environmental exposures have now been shown to increase the risk of ARDS and related adverse outcomes. How environmental factors impact the risk of developing ARDS is a growing and important field of research that should inform the care of individual patients as well as public health policy.

Keywords: Acute lung injury (ALI); Acute respiratory distress syndrome (ARDS); Environmental pollution; Tobacco smoke; Wildfires; e-cigarette and vaping-associated lung injury (EVALI); e-cigarettes.

Publication types

Review

MeSH terms

Humans
Incidence
Intensive Care Units
Respiratory Distress Syndrome* / etiology
Respiratory Distress Syndrome* / therapy

Abstract

Publication types

MeSH terms

Grants and funding