Methodological Rigor in Preclinical Cardiovascular Research: Contemporary Performance of AHA Scientific Publications

Richard G Jung; Cameron Stotts; Dwipen Makwana; Pouya Motazedian; Pietro Di Santo; Cheng-Yee Goh; Louis Verreault-Julien; Trevor Simard; F Daniel Ramirez; Benjamin Hibbert

doi:10.1161/CIRCRESAHA.121.319921

Methodological Rigor in Preclinical Cardiovascular Research: Contemporary Performance of AHA Scientific Publications

Circ Res. 2021 Oct 15;129(9):887-889. doi: 10.1161/CIRCRESAHA.121.319921. Epub 2021 Sep 15.

Authors

Richard G Jung^#^{1

2

3}, Cameron Stotts^#^{1

4}, Dwipen Makwana¹, Pouya Motazedian^{1

2

5

6}, Pietro Di Santo^{1

2

5

7}, Cheng-Yee Goh^{1

5}, Louis Verreault-Julien^{1

5}, Trevor Simard^{1

2

5

3

8}, F Daniel Ramirez^{1

5}, Benjamin Hibbert^{1

2

5

3}

Affiliations

¹ CAPITAL Research Group (R.G.J., C.S., D.M., P.M., P.D.S., C.-Y.G., L.V.-J., T.S., F.D.R., B.H.), University of Ottawa Heart Institute, Ontario, Canada.
² Vascular Biology and Experimental Medicine Laboratory (R.G.J., P.M., P.D.S., T.S., B.H.), University of Ottawa Heart Institute, Ontario, Canada.
³ Cellular and Molecular Medicine, Faculty of Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ontario, Canada.
⁴ Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine (C.S.), University of Ottawa, Ontario, Canada.
⁵ Division of Cardiology (P.M., P.D.S., C.-Y.G., L.V.-J., F.D.R., B.H.), University of Ottawa Heart Institute, Ontario, Canada.
⁶ Cumming School of Medicine, University of Calgary, Alberta, Canada (P.M.).
⁷ School of Epidemiology (P.D.S.), University of Ottawa, Ontario, Canada.
⁸ Department of Cardiovascular Diseases, Mayo Clinic School of Medicine, Rochester, MN (T.S.).

^# Contributed equally.

PMID: 34521221
DOI: 10.1161/CIRCRESAHA.121.319921

No abstract available

Keywords: animals; bias; hypertension; sample size; thrombosis.

Publication types

Letter

MeSH terms

American Heart Association*
Animals
Cardiovascular Diseases / physiopathology*
Disease Models, Animal
Periodicals as Topic / standards*
Periodicals as Topic / statistics & numerical data
Research Design / standards
Translational Research, Biomedical / standards*
Translational Research, Biomedical / statistics & numerical data
United States