A Novel Technique for Treating Early Deep Surgical Site Infection After Posterior Lumbar Fusion with Instrumentation

World Neurosurg. 2021 Dec:156:e167-e174. doi: 10.1016/j.wneu.2021.09.016. Epub 2021 Sep 10.

Abstract

Objective: To introduce a novel technique of using incisional vacuum-assisted closure (VAC) after 1-stage incision suture combined with closed suction irrigation system (CSIS) for treating early deep surgical site infection (SSI) after posterior lumbar fusion with instrumentation and to compare it with traditional CSIS.

Methods: This was a retrospective study. Patients with early deep SSI after posterior lumbar fusion with instrumentation from January 2013 to May 2020 who were treated by meticulous debridement followed by either CSIS or incisional VAC after 1-stage incision suture combined with CSIS were identified. The demographic characteristics, treatment features, and outcomes were analyzed and compared between the 2 treatment methods.

Results: A total of 48 patients (48/5016, 0.96%) developed early deep SSI, 46 of whom were enrolled in this study. This included 24 patients in the CSIS group (group 1) and 22 patients in the incisional VAC after 1-stage incision suture combined with CSIS group (group 2). All patients received follow-up, with an average of 19.7 months (range, 13-30 months). There were no significant differences in demographic characteristics in both groups (P > 0.05). The number of VAC foam dressing or ordinary dressing changes (P < 0.001), number of debridements (P = 0.028), intravenous antibiotic duration (P = 0.042), oral antibiotic duration (P = 0.019), and hospital stay (P = 0.029) in group 1 were significantly higher than those in group 2. The irrigation duration in group 1 was significantly shorter than that in group 2 (P = 0.007). All patients were eventually cured with satisfactory outcomes.

Conclusions: Compared with CSIS, incisional VAC after 1-stage incision suture combined with CSIS may be recommended considering that it has fewer dressing changes, fewer debridements, longer irrigation duration, shorter duration of antibiotic use, shorter hospital stay, and more convenient nursing care.

Keywords: 1-Stage incision suture; Closed suction irrigation system; Deep surgical site infection; Incisional vacuum-assisted closure; Posterior lumbar fusion with instrumentation.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use
  • Debridement
  • Female
  • Follow-Up Studies
  • Humans
  • Length of Stay
  • Lumbosacral Region
  • Male
  • Middle Aged
  • Negative-Pressure Wound Therapy / methods*
  • Retrospective Studies
  • Spinal Fusion / adverse effects*
  • Spinal Fusion / methods*
  • Suction
  • Surgical Wound Infection / therapy*
  • Sutures
  • Therapeutic Irrigation
  • Treatment Outcome
  • Wound Closure Techniques*

Substances

  • Anti-Bacterial Agents