Treatment options for leishmaniasis

Clin Exp Dermatol. 2022 Mar;47(3):516-521. doi: 10.1111/ced.14919. Epub 2021 Oct 20.

Abstract

Leishmaniasis is broadly classified into three types: cutaneous, mucocutaneous and visceral. The visceral form is most dangerous and can result in death. Although leishmaniasis is an ancient disease, its treatment is still challenging. Several drugs, differing in their cost, toxicity, treatment duration and emergence of drug resistance, are used for different types of leishmaniasis. To overcome these limitations, the search for newer drugs and other treatments continues. In this article, we discuss conventional drugs, other treatments, including newer options such as immunotherapy and immunochemotherapy, and future prospects for leishmaniasis treatment.

Publication types

  • Review

MeSH terms

  • Antiprotozoal Agents / therapeutic use
  • Combined Modality Therapy
  • Cryotherapy
  • Drug Therapy, Combination
  • Hot Temperature / therapeutic use
  • Humans
  • Immunotherapy
  • Leishmaniasis / drug therapy
  • Leishmaniasis / therapy*
  • Photochemotherapy

Substances

  • Antiprotozoal Agents