c-Myc regulates neural stem cell quiescence and activation by coordinating the cell cycle and mitochondrial remodeling

Chunhui Cai; Xinyu Hu; Peibin Dai; Tianran Zhang; Mei Jiang; Liefu Wang; Wanhao Hua; Yantao Fan; Xin-Xin Han; Zhengliang Gao

doi:10.1038/s41392-021-00664-7

c-Myc regulates neural stem cell quiescence and activation by coordinating the cell cycle and mitochondrial remodeling

Signal Transduct Target Ther. 2021 Aug 25;6(1):306. doi: 10.1038/s41392-021-00664-7.

Authors

Chunhui Cai^#^{1

2

3}, Xinyu Hu^#^{1

2

3}, Peibin Dai^#¹, Tianran Zhang¹, Mei Jiang¹, Liefu Wang⁴, Wanhao Hua^{1

2

3}, Yantao Fan^{1

2

3}, Xin-Xin Han⁵, Zhengliang Gao^{6

7

8}

Affiliations

¹ Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), Tongji University School of Medicine, Shanghai, China.
² Institute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People's Hospital of Nantong), School of Medicine, Shanghai University, Nantong, China.
³ Shanghai Engineering Research Center of Organ Repair, School of Medicine, Shanghai University, Shanghai, China.
⁴ Xinyang Vocational and Technical College, Xinyang, Henan, China.
⁵ Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Shanghai Stomatological Hospital, Fudan University, Shanghai, China. xxhan@fudan.edu.cn.
⁶ Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), Tongji University School of Medicine, Shanghai, China. zhengliang_gao@tongji.edu.cn.
⁷ Institute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People's Hospital of Nantong), School of Medicine, Shanghai University, Nantong, China. zhengliang_gao@tongji.edu.cn.
⁸ Xinyang Vocational and Technical College, Xinyang, Henan, China. zhengliang_gao@tongji.edu.cn.

^# Contributed equally.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cell Cycle*
Mice
Mice, Knockout
Mitochondria / genetics
Mitochondria / metabolism*
Neural Stem Cells / metabolism*
Proto-Oncogene Proteins c-myc / genetics
Proto-Oncogene Proteins c-myc / metabolism*

Substances

Myc protein, mouse
Proto-Oncogene Proteins c-myc