Clinical Outcomes and Antibody Response in COVID-19-Positive Pediatric Solid Organ Transplant Recipients

Pediatr Infect Dis J. 2021 Dec 1;40(12):e514-e516. doi: 10.1097/INF.0000000000003293.

Abstract

We describe the clinical and laboratory manifestations and outcomes of 25 pediatric solid organ transplant recipients who tested positive for severe acute respiratory coronavirus-2. Twenty-one (84%) developed a mild disease; 22 of 23 (96%) had a positive serologic response. Two patients (8%), both kidney transplant recipients with additional comorbidities, developed a severe disease. The findings emphasize the need for close monitoring of this population.

MeSH terms

  • Adolescent
  • Antibodies, Viral / blood*
  • COVID-19 / blood*
  • COVID-19 / complications*
  • Child
  • Female
  • Humans
  • Immunocompromised Host
  • Male
  • Organ Transplantation*
  • Retrospective Studies
  • SARS-CoV-2*
  • Transplant Recipients*

Substances

  • Antibodies, Viral