Right-sided endocarditis caused by polyclonal Staphylococcus aureus infection

Yotam Kolben; Yuval Ishay; Henny Azmanov; Assaf Rokney; Moti Baum; Sharon Amit; Ran Nir-Paz

doi:10.1186/s40001-021-00549-z

Right-sided endocarditis caused by polyclonal Staphylococcus aureus infection

Eur J Med Res. 2021 Aug 11;26(1):91. doi: 10.1186/s40001-021-00549-z.

Authors

Yotam Kolben¹, Yuval Ishay², Henny Azmanov², Assaf Rokney³, Moti Baum³, Sharon Amit⁴, Ran Nir-Paz⁴

Affiliations

¹ Department of Medicine, Hadassah Medical Organization and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel. yotamkol@hadassah.org.il.
² Department of Medicine, Hadassah Medical Organization and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
³ Government Central Laboratories, Ministry of Health, Jerusalem, Israel.
⁴ Department of Microbiology, Hadassah Medical Organization and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.

Abstract

We present a case of bacterial endocarditis with both methicillin-sensitive and methicillin-resistant Staphylococcus aureus, which based on typing, originated from two distinct clones. Such a case may be misinterpreted by microbiology lab automation to be a monoclonal multi-drug resistant Staphylococcus aureus, while simple microbiology techniques will instantly reveal distinct clonality.

Keywords: Endocarditis; Polyclonal infection; Staphylococcus aureus.

Publication types

Case Reports

MeSH terms

Adult
Coinfection
Drug Resistance, Bacterial
Endocarditis, Bacterial / microbiology*
Endocarditis, Bacterial / pathology
Humans
Male
Methicillin-Resistant Staphylococcus aureus / drug effects
Methicillin-Resistant Staphylococcus aureus / isolation & purification*
Methicillin-Resistant Staphylococcus aureus / pathogenicity
Staphylococcal Infections / microbiology*
Staphylococcal Infections / pathology