First Chinese case report of Helcococcus kunzii in a patient with diabetic foot

BMC Infect Dis. 2021 Jul 20;21(1):695. doi: 10.1186/s12879-021-06309-y.

Abstract

Background: Infection of Helcococcus kunzii(H. kunzii) from diabetic foot wound is rarely reported. This case report describes the infection of H.kunzii and highlights the therapeutic effect on H.kunzii from a diabetic foot wound.

Case presentation: In this study, one H. kunzii strain was isolated from a patient with diabetic foot, which was confirmed by 16S rRNA gene analysis and MALDI-TOF-MS. It is the first Chinese case of H. kunzii in a patient with diabetic foot. As a result of the lack of antibiotic sensitivity data and multiple comorbidities, antibiotics were used cautiously, and those administered during the first 3 months were ineffective. Then, vacuum sealing drainage (VSD) was applied during hospitalization; no antibiotics were used and the wound healed well.

Conclusions: VSD alone may be more effective in treating diabetic feet infected with H. kunzii, which may provide reference for clinical treatment of H. kunzii infection from diabetic foot.

Keywords: 16S rRNA gene sequencing; Case report; Diabetic foot; Helcococcus kunzii; MALDI-TOF-MS.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • China
  • Diabetic Foot / microbiology*
  • Diabetic Foot / therapy
  • Firmicutes / isolation & purification*
  • Gram-Positive Bacterial Infections / diagnosis*
  • Gram-Positive Bacterial Infections / microbiology*
  • Humans
  • Male
  • RNA, Ribosomal, 16S / genetics

Substances

  • RNA, Ribosomal, 16S

Supplementary concepts

  • Helcococcus kunzii