Non-arteritic anterior ischaemic optic neuropathy sequential to SARS-CoV-2 virus pneumonia: preventable by endothelial protection?

BMJ Case Rep. 2021 Jul 19;14(7):e240542. doi: 10.1136/bcr-2020-240542.

Abstract

We present a case of non-arteritic anterior ischaemic optic neuropathy (NAION) with no ocular or systemic risk factors in a patient who recovered from a recent SARS-CoV-2 pneumonia. NAION is the most common acute optic neuropathy among individuals over 50 years of age. It results from a transient hypoperfusion of the optic nerve head circulation, especially in patients with low vascular compliance due to ocular or systemic risk factors. We attribute the ophthalmological condition to a SARS-CoV-2 virus-associated endotheliopathy that can be prevented with timely protection of endothelial function with vitamins D and K2.

Keywords: COVID-19; capillary; cranial nerves; eye.

Publication types

  • Case Reports

MeSH terms

  • COVID-19*
  • Humans
  • Optic Disk*
  • Optic Nerve
  • Optic Neuropathy, Ischemic* / etiology
  • SARS-CoV-2