Olfactory Modulation of the Contingent Negative Variation to Auditory Stimuli

Abstract

Although pleasantness is intrinsically related to the perception of odors it is difficult to objectively assess odor-induced pleasantness. To evaluate the effects of odors of different valences on the contingent negative variation (CNV) in a younger and an older population. Data from 62 participants (27 men, 35 women) were included. Two age groups with Age group 1 (YOUNG) had 30 subjects within age 18-30 years and age group 2 (OLD) had 32 subjects with age >40 years. Pre-testing was performed to acquaint subjects with the experimental tasks and their environment. Subjects received "Sniffin' Sticks" odor identification tests and a standardized medical history to ascertain normosmia. In addition, they also took questionnaires relating to importance of the sense of smell and personality traits. CNV was elicited with two auditory stimuli, S1 followed by S2 at an interval of 2.4 s. Subjects were asked to push a button as fast as possible after they perceived S2. EEG was recorded from 4 positions of the 10-20 system (Fp2, Fz, Cz, and Pz). Four odors plus odorless air was presented in randomized order. The following main results emerged: (1) Consistent with the literature CNV showed a typical topographical distribution with the largest amplitude over the front-central recording sites. (2) 69% of subjects had consistent CNV for all conditions. (3) for some odor conditions CNV amplitudes exhibit a weak relation to odor pleasantness and associations with calmness. (4) CNV amplitude correlated negatively with reaction times. Overall, the results suggest the usefulness of CNV as an electrophysiological measure of cognition. However, in the present context, concomitantly applied odors of different hedonic tones exerted only minor effects on CNV. Thus, we conclude that odors have little or no effect on CNV.

Keywords: EEG; expectation; nose; pleasantness; smell; valence.