Hydroxyurea therapy decreases coagulation and endothelial activation in sickle cell disease: a Longitudinal Study

Br J Haematol. 2021 Aug;194(3):e71-e73. doi: 10.1111/bjh.17650. Epub 2021 Jul 6.

Laila Elsherif¹, Lara C Scott², David Wichlan³, Susan K Jones^{3

4}, Joacy G Mathias⁵, Jessica H Shen^{3

6}, Matthew P Smeltzer⁷, Kenneth I Ataga¹

¹ Center for Sickle Cell Disease, University of Tennessee Health Science Center, Memphis, TN, USA.
² College of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
³ Division of Hematology, University of North Carolina, Chapel Hill, NC, USA.
⁴ Division of Hematologic Malignancies and Cellular Therapy, Duke University School of Medicine, Durham, NC, USA.
⁵ Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.
⁶ School of Dentistry, Temple University, Philadelphia, PA, USA.
⁷ Division of Epidemiology, Biostatistics and Environmental Health, The University of Memphis, Memphis, TN, USA.

No abstract available

Keywords: coagulation activation; endothelial activation; hydroxycarbamide; inflammation; sickle cell disease.

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