Management of Helicobacter pylori infection: The Bhubaneswar Consensus Report of the Indian Society of Gastroenterology

Indian J Gastroenterol. 2021 Aug;40(4):420-444. doi: 10.1007/s12664-021-01186-4. Epub 2021 Jul 5.

Abstract

The Indian Society of Gastroenterology (ISG) felt the need to organize a consensus on Helicobacter pylori (H. pylori) infection and to update the current management of H. pylori infection; hence, ISG constituted the ISG's Task Force on Helicobacter pylori. The Task Force on H. pylori undertook an exercise to produce consensus statements on H. pylori infection. Twenty-five experts from different parts of India, including gastroenterologists, pathologists, surgeons, epidemiologists, pediatricians, and microbiologists participated in the meeting. The participants were allocated to one of following sections for the meeting: Epidemiology of H. pylori infection in India and H. pylori associated conditions; diagnosis; treatment and retreatment; H. pylori and gastric cancer, and H. pylori prevention/public health. Each group reviewed all published literature on H. pylori infection with special reference to the Indian scenario and prepared appropriate statements on different aspects for voting and consensus development. This consensus, which was produced through a modified Delphi process including two rounds of face-to-face meetings, reflects our current understanding and recommendations for the diagnosis and management of H. pylori infection. These consensus should serve as a reference for not only guiding treatment of H. pylori infection but also to guide future research on the subject.

Keywords: Antibiotic resistance; Duodenal ulcer; Gastric cancer; Gastritis; Helicobacter pylori eradication; Rescue therapies; Salvage therapy; Treatment failure; Treatment outcome.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Consensus
  • Drug Resistance, Microbial
  • Gastroenterology / standards*
  • Helicobacter Infections / diagnosis
  • Helicobacter Infections / drug therapy*
  • Helicobacter Infections / epidemiology
  • Helicobacter pylori / drug effects*
  • Humans
  • Salvage Therapy
  • Societies, Medical
  • Stomach Neoplasms / microbiology
  • Treatment Failure
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents