Directions of Deep Brain Stimulation for Epilepsy and Parkinson's Disease

Ying-Chang Wu; Ying-Siou Liao; Wen-Hsiu Yeh; Sheng-Fu Liang; Fu-Zen Shaw

doi:10.3389/fnins.2021.680938

Directions of Deep Brain Stimulation for Epilepsy and Parkinson's Disease

Front Neurosci. 2021 Jun 14:15:680938. doi: 10.3389/fnins.2021.680938. eCollection 2021.

Authors

Ying-Chang Wu¹, Ying-Siou Liao¹, Wen-Hsiu Yeh², Sheng-Fu Liang^{1

3}, Fu-Zen Shaw^{2

4}

Affiliations

¹ Department of Computer Science and Information Engineering, National Cheng Kung University, Tainan, Taiwan.
² Institute of Basic Medical Science, National Cheng Kung University, Tainan, Taiwan.
³ Institute of Medical Informatics, National Cheng Kung University, Tainan, Taiwan.
⁴ Department of Psychology, National Cheng Kung University, Tainan, Taiwan.

Abstract

Background: Deep brain stimulation (DBS) is an effective treatment for movement disorders and neurological/psychiatric disorders. DBS has been approved for the control of Parkinson disease (PD) and epilepsy.

Objectives: A systematic review and possible future direction of DBS system studies is performed in the open loop and closed-loop configuration on PD and epilepsy.

Methods: We searched Google Scholar database for DBS system and development. DBS search results were categorized into clinical device and research system from the open-loop and closed-loop perspectives.

Results: We performed literature review for DBS on PD and epilepsy in terms of system development by the open loop and closed-loop configuration. This study described development and trends for DBS in terms of electrode, recording, stimulation, and signal processing. The closed-loop DBS system raised a more attention in recent researches.

Conclusion: We overviewed development and progress of DBS. Our results suggest that the closed-loop DBS is important for PD and epilepsy.

Keywords: PD; closed-loop; deep brain stimulation; epilepsy; open loop.

Publication types

Review