A review of thromboembolic events in hospitalized COVID-19 patients

Paul Fontelo; Mrigendra M Bastola; Zhaonian Zheng; Seo Hyon Baik

doi:10.1186/s12959-021-00298-3

A review of thromboembolic events in hospitalized COVID-19 patients

Thromb J. 2021 Jun 29;19(1):47. doi: 10.1186/s12959-021-00298-3.

Authors

Paul Fontelo¹, Mrigendra M Bastola², Zhaonian Zheng², Seo Hyon Baik²

Affiliations

¹ Applied Clinical Informatics Branch, Lister Hill National Center for Biomedical Communications, National Library of Medicine, National Institutes of Health, 8600 Rockville Pike, Bethesda, MD, 20894, USA. pfontelo@nih.gov.
² Applied Clinical Informatics Branch, Lister Hill National Center for Biomedical Communications, National Library of Medicine, National Institutes of Health, 8600 Rockville Pike, Bethesda, MD, 20894, USA.

Abstract

Context: A higher incidence of thromboembolic disorders in COVID-19 has been reported by many clinicians worldwide.

Objective, design and data sources: Selected studies found in PubMed that reported thromboembolic events were included for meta-analysis using weighted fixed and random effects. Data from 19 articles on cohort studies in patients diagnosed with COVID-19 and thromboembolic events, including thrombosis and embolism were included in this review.

Results: The likelihood for developing thromboembolic disorders in hospitalized COVID-19 patients was 0.28 (95% CI 0.21-0.36).

Conclusion: This study further validates the increased risk of VTE in COVID-19 patients when compared to healthy, non-hospitalized people, and hospitalized patients. These findings will be useful to researchers and medical practitioners caring for COVID-19 patients.

Publication types

Review