Delivering embryos following 10 years of cryopreservation, using unpaired freeze/thaw techniques: A case report

JBRA Assist Reprod. 2021 Oct 4;25(4):644-646. doi: 10.5935/1518-0557.20210015.

Abstract

Although frozen embryo transfer is a widely established route for assisted reproduction, successful frozen embryo transfer using embryos that have undergone long term cryopreservation remains relatively unexplored, and its efficacy remains a matter of some debate. This case report describes two successful frozen embryo transfer conceptions in the same patient, one after 3 months of cryopreservation and the second 10 years after cryopreservation. These embryos were cryopreserved using the slow freezing technique and were thawed using an unpaired technique (ultra-rapid warming) after 10 years of storage.

Keywords: in vitro fertilization; long-term embryo cryopreservation; slow freezing; vitrification.

Publication types

  • Case Reports

MeSH terms

  • Cryopreservation*
  • Embryo Transfer*
  • Female
  • Fertilization
  • Freezing
  • Humans
  • Pregnancy
  • Pregnancy Rate