Getting toGether in Germinal centers

Sci Immunol. 2021 Jun 4;6(60):eabi9749. doi: 10.1126/sciimmunol.abi9749. Epub 2021 Jun 4.

Abstract

In this issue of Science Immunology, Gallman et al. reveal how S-geranylgeranyl-l-glutathione cleavage and transport support P2RY8-driven B cell confinement to the germinal centers and its role in lymphocyte homing to the bone marrow.

Publication types

  • Review
  • Comment

MeSH terms

  • B-Lymphocytes*
  • Bone Marrow
  • Germinal Center*
  • Glutathione
  • Lymphocytes

Substances

  • S-geranylgeranyl-L-glutathione
  • Glutathione