Changing Molecular Epidemiology of Hepatitis A Virus Infection, United States, 1996-2019

Emerg Infect Dis. 2021 Jun;27(6):1742-1745. doi: 10.3201/eid2706.203036.

Abstract

Hepatitis A virus (HAV) genotype IA was most common among strains tested in US outbreak investigations and surveillance during 1996-2015. However, HAV genotype IB gained prominence during 2016-2019 person-to-person multistate outbreaks. Detection of previously uncommon strains highlights the changing molecular epidemiology of HAV infection in the United States.

Keywords: Hepatitis A virus; United States; food safety; genotype; molecular surveillance; outbreaks; sexually transmitted infections; surveillance; technical assistance; viruses.

MeSH terms

  • Disease Outbreaks
  • Genotype
  • Hepatitis A virus* / genetics
  • Hepatitis A* / epidemiology
  • Humans
  • Molecular Epidemiology
  • Phylogeny
  • RNA, Viral
  • United States

Substances

  • RNA, Viral