Madelung's disease. Two case reports with pseudoathletic appearance

Clin Ter. 2021 May 5;172(3):190-192. doi: 10.7417/CT.2021.2311.

Abstract

Madelung's disease is a rare syndrome characterized by the pre-sence of multiple masses of unencapsulated adipose tissue, symme-trically distributed throughout different regions. It predominantly affects middle-aged men of Mediterranean origin with a history of alcoholism. The pathogenesis is still unknown. Diagnosis is essentially established through clinical history and physical examination. We report two cases for their unusual presentation and to emphasize the importance of early diagnosis.

Keywords: Launois-Bensaude syndrome; Madelung’s disease; benign sym-metric lipomatosis; cutaneous lipomatosis; multiple symmetric lipomatosis.

Publication types

  • Case Reports

MeSH terms

  • Adipose Tissue / pathology*
  • Alcoholism / complications
  • Female
  • Humans
  • Lipomatosis, Multiple Symmetrical / diagnosis*
  • Lipomatosis, Multiple Symmetrical / pathology
  • Male
  • Middle Aged
  • Syndrome